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Unraveling the SARS-CoV-2 Spike Protein: A New Hope for Systemic Detoxification

Aug 4, 2024

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In the wake of the COVID-19 pandemic, understanding and addressing the potential long-term effects of COVID-19 and its vaccines has become increasingly important. While vaccines have played a crucial role in controlling the spread of the virus, some individuals have reported lingering health issues post-vaccination. This has led to discussions on potential detoxification strategies to address symptoms associated with spike protein accumulation in the body.


The recent study by Anthony M. Kyriakopoulos, Greg Nigh, Peter A. McCullough, and Stephanie Seneff, published in the Journal of American Physicians and Surgeons, delves into a groundbreaking approach for tackling the lingering effects of the SARS-CoV-2 spike protein in the body. This protein, integral to both the COVID-19 virus and the mRNA vaccines, has been implicated in triggering severe inflammatory responses and various health complications. Here's a look into what the research reveals and the potential it holds for systemic detoxification.


The Spike Protein: A Persistent Problem

Recent reports and studies suggest that the SARS-CoV-2 spike protein is a foreign protein that remains in cells and tissues long after COVID-19 infection and vaccination, a key component in both the virus and the vaccine-induced immune response. This persistence can potentially lead to inflammation and other health complications. Its presence is associated with inflammatory responses, autoimmune attacks, and activation of the nuclear factor kappa light chain enhancer of activated B cells (NF-κB), impacting vital organs like the heart, lungs, brain, and kidneys. The spike protein's role in cardiovascular complications and severe outcomes such as cytokine storms is well-documented. Autopsy studies have shown that spike proteins can accumulate in various organs, including the heart, brain, liver, and ovaries, potentially contributing to adverse events such as myocarditis, cardiac arrhythmias, and thrombotic events.


Addressing Spike Protein-Related Complications

The persistence of spike proteins post-infection or vaccination raises significant health concerns. For instance, these proteins can cross the blood-brain barrier, inciting neuroinflammation and affecting the central nervous system. The authors emphasize the urgency of developing therapies to detoxify the body from these proteins, especially in conditions like long COVID and vaccine injury syndromes.


Proteolytic Enzymes: A Promising Solution

The study highlights the potential of proteolytic enzymes derived from natural sources to degrade the spike protein, thus mitigating its harmful effects. These enzymes could serve as a non-toxic therapeutic approach for managing spike protein-related pathologies.

Key Proteolytic Enzymes Discussed:
  1. Nattokinase (NK):

  • Origin: Found in natto, a traditional Japanese soybean food.

  • Function: NK is a fibrinolytic enzyme that can degrade fibrins and viral proteins. Studies have shown its effectiveness in degrading the SARS-CoV-2 spike protein, including its receptor binding domain (RBD), in a dose-dependent manner without harming cells.

  1. Alkaline Serine Protease (ASPNJ):

  • Origin: Extracted from the Neanthes jabonika worm.

  • Function: ASPNJ specifically cleaves regions in the spike protein, reducing its ability to interact with human cells. It shows promise in degrading both full-length spike proteins and subunits, potentially offering therapeutic benefits against new viral variants.

  1. Serratiopeptidase (SEPD):

  • Applications: Known for its anti-inflammatory and mucolytic properties, SEPD has shown potential in enhancing immune defenses and mitigating inflammation caused by spike proteins.


Dr. Peter McCullough’s Detoxification Protocol

Dr. Peter McCullough, a prominent cardiologist, has proposed a detoxification protocol aimed at reducing spike protein levels in the body. This protocol includes:

  • Nattokinase: 2000 FU (100 mg) orally twice a day without food. Nattokinase is an enzyme that may support healthy blood flow and circulation by promoting fibrinolytic activity.

  • Bromelain: 500 mg orally once a day without food. Bromelain, an enzyme from the pineapple plant, aids in digestion and supports musculoskeletal health by maintaining healthy kinin and fibrin production.

  • Curcumin: 500 mg orally twice a day (nano, liposomal, or with piperine additive suggested). Curcumin is known for its anti-inflammatory properties and supports cellular health. Bioperine, a black pepper extract, is included to enhance curcumin absorption.


Potential Impact on Health

The therapeutic use of these proteolytic enzymes could revolutionize the management of COVID-19-related complications. Their ability to degrade spike proteins, reduce inflammation, and potentially prevent neurodegenerative effects offers a multifaceted approach to addressing both acute and chronic conditions associated with the virus and its vaccine.


Considerations and Recommendations

While Dr. McCullough’s protocol offers a promising approach to spike protein detoxification, it is essential to note that these supplements have not been tested in large-scale clinical trials. As such, individuals considering this regimen should consult with healthcare providers, especially regarding potential bleeding risks and allergic reactions.


Dr. Frank Yap, M.D., emphasizes the importance of clinical trials for detoxification protocols but supports pursuing empiric therapy when trials are not available. Patients are encouraged to discuss these options with their doctors and advocate for referral to clinical trials whenever possible.


Accessing Supplements

Nattokinase, Bromelain, and Curcumin are available as over-the-counter supplements. Patients interested in following Dr. McCullough’s protocol can purchase these supplements online or in health stores. It's crucial to ensure that the chosen supplements are of high quality and sourced from reputable manufacturers.


Conclusion

As we continue to navigate the aftermath of the COVID-19 pandemic, exploring treatments and protocols that address post-vaccination symptoms is vital. Dr. McCullough’s spike protein detoxification protocol represents a potential strategy for individuals experiencing prolonged health issues post-vaccination. While more research is needed, this protocol offers a starting point for those seeking to alleviate symptoms associated with spike protein accumulation.


The study underscores the need for clinical trials to further explore and validate the efficacy and safety of these proteolytic enzymes in humans. By repurposing existing enzymes and introducing new ones like NK, ASPNJ, and SEPD, there is hope for developing effective therapies against spike protein-associated pathologies, thereby alleviating the long-term impacts of COVID-19 and mRNA vaccinations. As research progresses, these natural agents could become a vital tool in our arsenal against pandemic-induced health challenges.


Incorporating these insights into therapeutic protocols could pave the way for safer, more effective management of post-COVID-19 and vaccine-related health issues, offering renewed hope for recovery and health optimization.


  • Dach, J. Spike Protein Detoxification Protocol of Dr Peter McCullough.

  • Hulscher, N., Procter, B. C., Wynn, C., & McCullough, P. A. (2023). Clinical approach to post-acute sequelae after COVID-19 infection and vaccination. Cureus, 15(11).

  • Kyriakopoulos, A. M., & Seneff, S. (2023). Proteolytic targets for SARS-CoV-2 spike protein degradation: Hope for systemic detoxification. Journal of American Physicians and Surgeons, 28(3), 86-93.

  • McCullough, P. A., Wynn, C., & Procter, B. C. (2023). Clinical rationale for SARS-CoV-2 base spike protein detoxification in post COVID-19 and vaccine injury syndromes. J Am Physicians Surg, 28, 90-93.

Aug 4, 2024

4 min read

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11

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